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The methodology of systematic reviews—although laid out three or more decades ago—is continuously and rapidly updated by scientists specializing in research synthesis. Now, Systematic Reviews is publishing a series of articles including methods and examples of accelerating approaches to conducting literature reviews. To read through the editorial and the upcoming series of papers, review the following link:



  1. Mulrow CD, Cook DJ, Davidoff F. Systematic reviews: critical links in the great chain of
    evidence. Ann Intern Med. 1997;126(5):389–91.

  2. Cook DJ, Mulrow CD, Haynes RB. Systematic reviews: synthesis of best evidence for
    clinical decisions. Ann Intern Med. 1997;126(5):376–80.

  3. Higgins JPT, Green S, editors. Cochrane handbook for systematic reviews of interventions
    version 5.1.0 (updated March 2011). The Cochrane Collaboration; 2011. Available from